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Cigarette smoke extract stimulates PCSK9 production in HepG2 cells via ROS/NF-κB signaling
Cigarette smoke (CS) exposure is a risk factor for dyslipidemia and atherosclerosis. Reduced expression of low-density lipoprotein receptor (LDLR) in hepatocytes may be one of the underlying mechanisms for these disorders. The aim of the present study was to investigate the molecular mechanism under...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974406/ https://www.ncbi.nlm.nih.gov/pubmed/33760160 http://dx.doi.org/10.3892/mmr.2021.11970 |