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The effect of anti-HLA class I antibodies on the immunological properties of human glomerular endothelial cells and their modification by mTOR inhibition or GCN2 kinase activation

In antibody-mediated rejection (ABMR), the graft endothelium is at the forefront of the kidney transplant against the assault from the recipient's humoral immune system, and is a target of the latter. The present study investigated the effect of antibodies against human leukocyte antigen (HLA)...

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Detalles Bibliográficos
Autores principales: Eleftheriadis, Theodoros, Pissas, Georgios, Crespo, Marta, Filippidis, Georgios, Antoniadis, Nikolaos, Liakopoulos, Vassilios, Stefanidis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974416/
https://www.ncbi.nlm.nih.gov/pubmed/33760196
http://dx.doi.org/10.3892/mmr.2021.11994