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Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation

Hepatic fibrosis, a common pathological manifestation of chronic liver injury, is generally considered to be the end result of an increase in extracellular matrix produced by activated hepatic stellate cells (HSCs). The aim of the present study was to target the mechanisms underlying HSC activation...

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Detalles Bibliográficos
Autores principales: Huang, He-Ming, Zhou, Xiao-Ru, Liu, Yan-Jun, Fan, Shi-Jie, Liao, Li-Ping, Huang, Jing, Shi, Cui-Cui, Yu, Liang, Pen, Jin-Jin, Luo, Cheng, Zhang, Yuan-Yuan, Li, Guang-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974418/
https://www.ncbi.nlm.nih.gov/pubmed/33649839
http://dx.doi.org/10.3892/mmr.2021.11944