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Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation
Hepatic fibrosis, a common pathological manifestation of chronic liver injury, is generally considered to be the end result of an increase in extracellular matrix produced by activated hepatic stellate cells (HSCs). The aim of the present study was to target the mechanisms underlying HSC activation...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974418/ https://www.ncbi.nlm.nih.gov/pubmed/33649839 http://dx.doi.org/10.3892/mmr.2021.11944 |