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Brucine inhibits proliferation of glioblastoma cells by targeting the G-quadruplexes in the c-Myb promoter
The proto-oncogene c-Myb plays an important role in cell proliferation, and its upregulation affects the development of glioblastomas. G-quadruplexes are secondary DNA or RNA structures that usually form in the promoter region of oncogenes, including c-Myb, and regulate the expression of these genes...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Ivyspring International Publisher
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974541/ https://www.ncbi.nlm.nih.gov/pubmed/33753997 http://dx.doi.org/10.7150/jca.53689 |