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Fast effect size shrinkage software for beta-binomial models of allelic imbalance

Allelic imbalance occurs when the two alleles of a gene are differentially expressed within a diploid organism and can indicate important differences in cis-regulation and epigenetic state across the two chromosomes. Because of this, the ability to accurately quantify the proportion at which each al...

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Detalles Bibliográficos
Autores principales: Zitovsky, Joshua P., Love, Michael I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974632/
https://www.ncbi.nlm.nih.gov/pubmed/33796271
http://dx.doi.org/10.12688/f1000research.20916.2