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Fast effect size shrinkage software for beta-binomial models of allelic imbalance
Allelic imbalance occurs when the two alleles of a gene are differentially expressed within a diploid organism and can indicate important differences in cis-regulation and epigenetic state across the two chromosomes. Because of this, the ability to accurately quantify the proportion at which each al...
Autores principales: | Zitovsky, Joshua P., Love, Michael I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974632/ https://www.ncbi.nlm.nih.gov/pubmed/33796271 http://dx.doi.org/10.12688/f1000research.20916.2 |
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