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β-elemene enhances the antitumor activity of erlotinib by inducing apoptosis through AMPK and MAPK pathways in TKI-resistant H1975 lung cancer cells

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) significantly improve the outcome of non-small-cell lung cancer (NSCLC) patients with EGFR mutations, however, most TKI-treated patients will develop resistance to TKIs. β-elemene, extracted from Curcuma aromatica Salisb., has...

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Detalles Bibliográficos
Autores principales: Wang, Jue, Xu, Cong, Chen, Ying, Shao, Le, Li, Ting, Fan, Xingxing, Yu, Lili, Zhang, Ruonan, Chen, Bi, Chen, Hongwei, Sui, Xinbing, Leung, Elaine Lai-Han, Wu, Qibiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974887/
https://www.ncbi.nlm.nih.gov/pubmed/33758606
http://dx.doi.org/10.7150/jca.53382