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The development and kinetics of functional antibody-dependent cell-mediated cytotoxicity (ADCC) to SARS-CoV-2 spike protein

Since the COVID-19 pandemic, functional non-neutralizing antibody responses to SARS-CoV-2, including antibody-dependent cell-mediated cytotoxicity (ADCC), are poorly understood. We developed an ADCC assay utilizing a stably transfected, dual-reporter target cell line with inducible expression of a S...

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Detalles Bibliográficos
Autores principales: Chen, Xuemin, Rostad, Christina A., Anderson, Larry J., Sun, He-ying, Lapp, Stacey A., Stephens, Kathy, Hussaini, Laila, Gibson, Theda, Rouphael, Nadine, Anderson, Evan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975276/
https://www.ncbi.nlm.nih.gov/pubmed/33774551
http://dx.doi.org/10.1016/j.virol.2021.03.009