Mechanistic Basis for In Vivo Therapeutic Efficacy of CK2 Inhibitor CX-4945 in Acute Myeloid Leukemia

SIMPLE SUMMARY: Acute Myeloid Leukemia is an aggressive disease with poor outcomes. New targeted therapies that can boost the effects of currently used chemotherapy medications without added toxicity are needed. Targeting an overactive kinase, called the protein Kinase CK2 in AML, helps leukemia cel...

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Detalles Bibliográficos
Autores principales: Klink, Morgann, Rahman, Mohammad Atiqur, Song, Chunhua, Dhanyamraju, Pavan Kumar, Ehudin, Melanie, Ding, Yali, Steffens, Sadie, Bhadauria, Preeti, Iyer, Soumya, Aliaga, Cesar, Desai, Dhimant, Huang, Suming, Claxton, David, Sharma, Arati, Gowda, Chandrika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975325/
https://www.ncbi.nlm.nih.gov/pubmed/33807974
http://dx.doi.org/10.3390/cancers13051127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975325/
https://www.ncbi.nlm.nih.gov/pubmed/33807974
http://dx.doi.org/10.3390/cancers13051127

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