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miR-26b enhances the sensitivity of hepatocellular carcinoma to Doxorubicin via USP9X-dependent degradation of p53 and regulation of autophagy

Multi-drug resistance is a major challenge to hepatocellular carcinoma (HCC) treatment, and the over-expression or deletion of microRNA (miRNA) expression is closely related to the drug-resistant properties of various cell lines. However, the underlying molecular mechanisms remain unclear. CCK-8, Ed...

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Detalles Bibliográficos
Autores principales: Chen, Enjiang, Li, Enliang, Liu, Hao, Zhou, Yue, Wen, Liang, Wang, Jianxin, Wang, Yi, Ye, Longyun, Liang, Tingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975695/
https://www.ncbi.nlm.nih.gov/pubmed/33767588
http://dx.doi.org/10.7150/ijbs.52517