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miR-26b enhances the sensitivity of hepatocellular carcinoma to Doxorubicin via USP9X-dependent degradation of p53 and regulation of autophagy
Multi-drug resistance is a major challenge to hepatocellular carcinoma (HCC) treatment, and the over-expression or deletion of microRNA (miRNA) expression is closely related to the drug-resistant properties of various cell lines. However, the underlying molecular mechanisms remain unclear. CCK-8, Ed...
Autores principales: | Chen, Enjiang, Li, Enliang, Liu, Hao, Zhou, Yue, Wen, Liang, Wang, Jianxin, Wang, Yi, Ye, Longyun, Liang, Tingbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975695/ https://www.ncbi.nlm.nih.gov/pubmed/33767588 http://dx.doi.org/10.7150/ijbs.52517 |
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