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MLKL inhibits intestinal tumorigenesis by suppressing STAT3 signaling pathway

Mixed lineage kinase domain-like protein (MLKL) plays an important role in necroptosis, but the role and mechanism of MLKL in intestinal tumorigenesis remain unclear. Here, we found that hematopoietic- and nonhematopoietic-derived MLKL affected intestinal inflammation, but nonhematopoietic-derived M...

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Detalles Bibliográficos
Autores principales: Zhao, Qun, Cheng, Xinran, Guo, Jian, Bi, Yun, Kuang, Li, Ren, Jianhua, Zhong, Jing, Pan, Longrui, Zhang, Xudong, Guo, Yang, Liu, Yongqiang, Jin, Shu, Tan, Yan, Yu, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975698/
https://www.ncbi.nlm.nih.gov/pubmed/33767595
http://dx.doi.org/10.7150/ijbs.56152