The G1 phase optical reporter serves as a sensor of CDK4/6 inhibition in vivo

Visualization of cell-cycle G1 phase for monitoring the early response of cell cycle specific drug remains challenging. In this study, we developed genetically engineered bioluminescent reporters by fusing full-length cyclin E to the C-terminal luciferase (named as CycE-Luc and CycE-Luc2). Next, HeL...

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Detalles Bibliográficos
Autores principales: Guo, Cuiping, Guo, Yuxian, Liu, Jingjing, Gao, Yiyang, Wei, Min, Zhao, Ruijun, Chen, Min, Zhang, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975702/
https://www.ncbi.nlm.nih.gov/pubmed/33767584
http://dx.doi.org/10.7150/ijbs.52101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975702/
https://www.ncbi.nlm.nih.gov/pubmed/33767584
http://dx.doi.org/10.7150/ijbs.52101

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