IP6K2 predicts favorable clinical outcome of primary breast cancer

The inositol hexakisphosphate kinase (IP6K) 1 and 2 genes are localized at 3p21.31, a highly altered gene-dense chromosomal region in cancer. The IP6Ks convert IP6 to IP7, which inhibits activation of the tumor-promoting PI3K/Akt/mTOR signaling pathway. IP6K2 has been suggested to be involved in p53...

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Detalles Bibliográficos
Autores principales: Sandström, Josefine, Balian, Alien, Lockowandt, Rebecca, Fornander, Tommy, Nordenskjöld, Bo, Lindström, Linda, Pérez-Tenorio, Gizeh, Stål, Olle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7976380/
https://www.ncbi.nlm.nih.gov/pubmed/33767863
http://dx.doi.org/10.3892/mco.2021.2256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7976380/
https://www.ncbi.nlm.nih.gov/pubmed/33767863
http://dx.doi.org/10.3892/mco.2021.2256

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