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Granzyme family acts as a predict biomarker in cutaneous melanoma and indicates more benefit from anti-PD-1 immunotherapy

The incidence of cutaneous melanoma (CM) increased since the 1970s, and also along with an unfavorable prognosis. CM patients have been verified benefits from immunotherapy, and granzymes (GZMs) comprise more than 90% of the cytolytic granules secreted by cytotoxic T lymphocytes and nature killer ce...

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Detalles Bibliográficos
Autores principales: Wu, Xia, Wang, Xiaojie, Zhao, Yan, Li, Kun, Yu, Bo, Zhang, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7976569/
https://www.ncbi.nlm.nih.gov/pubmed/33746582
http://dx.doi.org/10.7150/ijms.54747