Synthesis and Characterization of Macrocyclic Chiral Tröger’s Base Phenhomazine Candidates as Anticancer Agent

1,4,7,10-Tetraoxa[10](2,8)trögerophane 5 was synthesized from its corresponding precursors. Heating of 2 with p-nitrophenoxide afforded bis(p-nitrophenyl)ether 3, which was treated with hydrazine hydrate to give bis(p-aminophenyl)ether 4. Treatment of 4 with paraformaldehyde and triflouroacetic anhy...

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Detalles Bibliográficos
Autores principales: Ibrahim, Alhussein A., Ali, Korany A., Hafez, Naglaa A. Abdel, Elsayed, Mohamed A., Mohamed, Khalid M. H., Hosni, Hanaa M., Amr, Abd El-Galil E., Elsayed, Elsayed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7976657/
https://www.ncbi.nlm.nih.gov/pubmed/33748073
http://dx.doi.org/10.3389/fchem.2020.633065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7976657/
https://www.ncbi.nlm.nih.gov/pubmed/33748073
http://dx.doi.org/10.3389/fchem.2020.633065

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