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Synthesis and Characterization of Macrocyclic Chiral Tröger’s Base Phenhomazine Candidates as Anticancer Agent
1,4,7,10-Tetraoxa[10](2,8)trögerophane 5 was synthesized from its corresponding precursors. Heating of 2 with p-nitrophenoxide afforded bis(p-nitrophenyl)ether 3, which was treated with hydrazine hydrate to give bis(p-aminophenyl)ether 4. Treatment of 4 with paraformaldehyde and triflouroacetic anhy...
Autores principales: | Ibrahim, Alhussein A., Ali, Korany A., Hafez, Naglaa A. Abdel, Elsayed, Mohamed A., Mohamed, Khalid M. H., Hosni, Hanaa M., Amr, Abd El-Galil E., Elsayed, Elsayed A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7976657/ https://www.ncbi.nlm.nih.gov/pubmed/33748073 http://dx.doi.org/10.3389/fchem.2020.633065 |
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