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Tumour cells express functional lymphatic endothelium-specific hyaluronan receptor in vitro and in vivo: Lymphatic mimicry promotes oral oncogenesis?

Lymphatic metastasis represents the main route of tumour cell dissemination in oral squamous cell carcinoma (OSCC). Yet, there are no FDA-approved therapeutics targeting cancer-related lymphangiogenesis to date. The lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE-1), a specific lymphat...

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Detalles Bibliográficos
Autores principales: Karinen, Sini, Juurikka, Krista, Hujanen, Roosa, Wahbi, Wafa, Hadler-Olsen, Elin, Svineng, Gunbjørg, Eklund, Kari K., Salo, Tuula, Åström, Pirjo, Salem, Abdelhakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977063/
https://www.ncbi.nlm.nih.gov/pubmed/33674563
http://dx.doi.org/10.1038/s41389-021-00312-3