Eribulin, Child-Pugh score, and liver-function tests: lessons from pivotal breast cancer studies 301 and 305

BACKGROUND: The recommended starting dose of eribulin in patients with hepatic impairment is based on the Child-Pugh score, largely informed by a pharmacokinetic study of 18 patients. In the pivotal studies of eribulin in metastatic breast cancer (Study 301 and Study 305 [EMBRACE]), entry criteria a...

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Detalles Bibliográficos
Autores principales: Macpherson, Iain R., He, Yaohua, Palmieri, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977154/
https://www.ncbi.nlm.nih.gov/pubmed/33736675
http://dx.doi.org/10.1186/s13058-021-01407-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977154/
https://www.ncbi.nlm.nih.gov/pubmed/33736675
http://dx.doi.org/10.1186/s13058-021-01407-w

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