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Signal amplification and optimization of riboswitch-based hybrid inputs by modular and titratable toehold switches

BACKGROUND: Synthetic biological circuits are widely utilized to control microbial cell functions. Natural and synthetic riboswitches are attractive sensor modules for use in synthetic biology applications. However, tuning the fold-change of riboswitch circuits is challenging because a deep understa...

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Detalles Bibliográficos
Autores principales: Hwang, Yunhee, Kim, Seong Gyeong, Jang, Sungho, Kim, Jongmin, Jung, Gyoo Yeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977183/
https://www.ncbi.nlm.nih.gov/pubmed/33741029
http://dx.doi.org/10.1186/s13036-021-00261-w