Histone deacetylase 3 inhibition alleviates type 2 diabetes mellitus-induced endothelial dysfunction via Nrf2

BACKGROUND: The mechanism underlying endothelial dysfunction leading to cardiovascular disease in type 2 diabetes mellitus (T2DM) remains unclear. Here, we show that inhibition of histone deacetylase 3 (HDAC3) reduced inflammation and oxidative stress by regulating nuclear factor-E2-related factor 2...

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Detalles Bibliográficos
Autores principales: Huang, Shuai, Chen, Gen, Sun, Jia, Chen, Yunjie, Wang, Nan, Dong, Yetong, Shen, Enzhao, Hu, Zhicheng, Gong, Wenjie, Jin, Litai, Cong, Weitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977318/
https://www.ncbi.nlm.nih.gov/pubmed/33736642
http://dx.doi.org/10.1186/s12964-020-00681-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977318/
https://www.ncbi.nlm.nih.gov/pubmed/33736642
http://dx.doi.org/10.1186/s12964-020-00681-z

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