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Charge-switchable zwitterionic polycarboxybetaine particle as an intestinal permeation enhancer for efficient oral insulin delivery

Insulin, a peptide hormone, is one of the most common and effective antidiabetic drugs. Although oral administration is considered to be the most convenient and safe choice for patients, the oral bioavailability of insulin is very low due to the poor oral absorption into blood circulation. Intestina...

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Detalles Bibliográficos
Autores principales: Li, Yan, Ji, Weihong, Peng, Huan, Zhao, Ruichen, Zhang, Tianlu, Lu, Zhiguo, Yang, Jun, Liu, Ruiyuan, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977443/
https://www.ncbi.nlm.nih.gov/pubmed/33754071
http://dx.doi.org/10.7150/thno.54176