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LncRNA PRADX-mediated recruitment of PRC2/DDX5 complex suppresses UBXN1 expression and activates NF-κB activity, promoting tumorigenesis

Rationale: Accumulating evidence indicates that long noncoding RNAs (lncRNAs) play crucial roles in cancer progression; however, only few have been characterized in detail. The current study aimed to identify a novel cancer driver lncRNA in glioblastoma and colon adenocarcinoma. Methods: We performe...

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Detalles Bibliográficos
Autores principales: Li, Yansheng, Liu, Xing, Cui, Xiaoteng, Tan, Yanli, Wang, Qixue, Wang, Yunfei, Xu, Can, Fang, Chuan, Kang, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977445/
https://www.ncbi.nlm.nih.gov/pubmed/33754075
http://dx.doi.org/10.7150/thno.54549