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SPTBN1 inhibits inflammatory responses and hepatocarcinogenesis via the stabilization of SOCS1 and downregulation of p65 in hepatocellular carcinoma

Background: Spectrin, beta, non-erythrocytic 1 (SPTBN1), an adapter protein for transforming growth factor beta (TGF-β) signaling, is recognized as a tumor suppressor in the development of hepatocellular carcinoma (HCC); however, the underlying molecular mechanisms of this tumor suppression remain o...

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Detalles Bibliográficos
Autores principales: Lin, Ling, Chen, Shuyi, Wang, Hua, Gao, Bin, Kallakury, Bhaskar, Bhuvaneshwar, Krithika, Cahn, Katherine, Gusev, Yuriy, Wang, Xue, Wu, Yunan, Marshall, John L., Zhi, Xiuling, He, Aiwu Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977457/
https://www.ncbi.nlm.nih.gov/pubmed/33754058
http://dx.doi.org/10.7150/thno.49819