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Redox-sensitive carrier-free nanoparticles self-assembled by disulfide-linked paclitaxel-tetramethylpyrazine conjugate for combination cancer chemotherapy

Rationale: Combinations of two or more therapeutic agents targeting different signaling pathways involved in tumor progression can have synergistic anticancer effects. However, combination chemotherapies are greatly limited by the different pharmacokinetics, tumor targeting, and cellular uptake capa...

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Detalles Bibliográficos
Autores principales: Zou, Liang, Liu, Xiaowei, Li, Jingjing, Li, Wei, Zhang, Lele, Fu, Chaomei, Zhang, Jinming, Gu, Zhongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977472/
https://www.ncbi.nlm.nih.gov/pubmed/33754055
http://dx.doi.org/10.7150/thno.42260