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Pancreatic ductal deletion of S100A9 alleviates acute pancreatitis by targeting VNN1-mediated ROS release to inhibit NLRP3 activation

Recent studies have proven that the overall pathophysiology of pancreatitis involves not only the pancreatic acinar cells but also duct cells, however, pancreatic duct contribution in acinar cells homeostasis is poorly known and the molecular mechanisms leading to acinar insult and acute pancreatiti...

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Detalles Bibliográficos
Autores principales: Xiang, Hong, Guo, Fangyue, Tao, Xufeng, Zhou, Qi, Xia, Shilin, Deng, Dawei, Li, Lunxu, Shang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977474/
https://www.ncbi.nlm.nih.gov/pubmed/33754072
http://dx.doi.org/10.7150/thno.54245