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FGF19/SOCE/NFATc2 signaling circuit facilitates the self-renewal of liver cancer stem cells

Background & Aims: Liver cancer stem cells (LCSCs) mediate therapeutic resistance and correlate with poor outcomes in patients with hepatocellular carcinoma (HCC). Fibroblast growth factor (FGF)-19 is a crucial oncogenic driver gene in HCC and correlates with poor prognosis. However, whether FGF...

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Detalles Bibliográficos
Autores principales: Wang, Jingchun, Zhao, Huakan, Zheng, Lu, Zhou, Yu, Wu, Lei, Xu, Yanquan, Zhang, Xiao, Yan, Guifang, Sheng, Halei, Xin, Rong, Jiang, Lu, Lei, Juan, Zhang, Jiangang, Chen, Yu, Peng, Jin, Chen, Qian, Yang, Shuai, Yu, Kun, Li, Dingshan, Xie, Qichao, Li, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978301/
https://www.ncbi.nlm.nih.gov/pubmed/33754043
http://dx.doi.org/10.7150/thno.56369