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Peripheral eosinophil counts predict efficacy of anti-CD19 CAR-T cell therapy against B-lineage non-Hodgkin lymphoma

Rationale: The onset of cytokine release syndrome (CRS) and in vivo persistence of anti-CD19 chimeric antigen receptor T (CAR-T) cells after infusion correlate with clinical responsiveness. However, there are no known baseline biomarkers that can predict the prognosis of patients with B-lineage non-...

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Detalles Bibliográficos
Autores principales: Jia, Qingzhu, Qin, Diyuan, He, Feng, Xie, Qichao, Ying, Zhitao, Zhang, Yajing, Song, Yuqin, Cheng, Jia-Nan, Zuo, Xuejiao, Xu, Luxiang, Fang, Hongliang, Hu, Chunyan, Peng, Lina, Jin, Tao, Shi, Zixiao, Alexander, Peter B., Wang, Yongsheng, Liu, Yarong, Han, Weidong, Zhu, Jun, Wang, Pin, Li, Qi-Jing, Zhu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978305/
https://www.ncbi.nlm.nih.gov/pubmed/33754022
http://dx.doi.org/10.7150/thno.54546