Cargando…
Synthesis of RNA-based gene regulatory devices for redirecting cellular signaling events mediated by p53
Rationale: The p53 gene is a well-known tumor suppressor, and its mutation often contributes to the occurrence and development of tumors. Due to the diversity and complexity of p53 mutations, there is still no effective p53 gene therapy. In this study, we designed and constructed an aptazyme switch...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Ivyspring International Publisher
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978309/ https://www.ncbi.nlm.nih.gov/pubmed/33754021 http://dx.doi.org/10.7150/thno.55856 |