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Deciphering the autophagy regulatory network via single-cell transcriptome analysis reveals a requirement for autophagy homeostasis in spermatogenesis

Background: Autophagy has been implicated as a crucial component in spermatogenesis, and autophagy dysfunction can lead to reproductive disorders in animal models, including yeast, C. elegans and mice. However, the sophisticated transcriptional networks of autophagic genes throughout human spermatog...

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Detalles Bibliográficos
Autores principales: Wang, Mei, Xu, Yanwen, Zhang, Yuncong, Chen, Yuhan, Chang, Gang, An, Geng, Yang, Xinyan, Zheng, Caihong, Zhao, Jiexiang, Liu, Zhaoting, Wang, Dazhuang, Miao, Kai, Rao, Shuan, Dai, Meng, Wang, Dong, Zhao, Xiao-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978313/
https://www.ncbi.nlm.nih.gov/pubmed/33754041
http://dx.doi.org/10.7150/thno.55645