Targeting lysosomal cysteine protease cathepsin S reveals immunomodulatory therapeutic strategy for oxaliplatin-induced peripheral neuropathy

Rationale: Oxaliplatin-induced peripheral neuropathy (OIPN) is a common adverse effect that causes delayed treatment and poor prognosis among colorectal cancer (CRC) patients. However, its mechanism remains elusive, and no effective treatment is available. Methods: We employed a prospective cohort s...

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Detalles Bibliográficos
Autores principales: Chen, Szu-Jung, Chen, Li-Hsien, Yeh, Yu-Min, Lin, Chou-Ching K, Lin, Peng-Chan, Huang, Han-Wei, Shen, Meng-Ru, Lin, Bo-Wen, Lee, Jeng-Chang, Lee, Cheng-Che, Lee, Yueh-Feng, Chiang, Huai-Chueh, Chang, Jang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978314/
https://www.ncbi.nlm.nih.gov/pubmed/33754020
http://dx.doi.org/10.7150/thno.54793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978314/
https://www.ncbi.nlm.nih.gov/pubmed/33754020
http://dx.doi.org/10.7150/thno.54793

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