Cargando…
Targeting lysosomal cysteine protease cathepsin S reveals immunomodulatory therapeutic strategy for oxaliplatin-induced peripheral neuropathy
Rationale: Oxaliplatin-induced peripheral neuropathy (OIPN) is a common adverse effect that causes delayed treatment and poor prognosis among colorectal cancer (CRC) patients. However, its mechanism remains elusive, and no effective treatment is available. Methods: We employed a prospective cohort s...
Autores principales: | Chen, Szu-Jung, Chen, Li-Hsien, Yeh, Yu-Min, Lin, Chou-Ching K, Lin, Peng-Chan, Huang, Han-Wei, Shen, Meng-Ru, Lin, Bo-Wen, Lee, Jeng-Chang, Lee, Cheng-Che, Lee, Yueh-Feng, Chiang, Huai-Chueh, Chang, Jang-Yang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978314/ https://www.ncbi.nlm.nih.gov/pubmed/33754020 http://dx.doi.org/10.7150/thno.54793 |
Ejemplares similares
-
The lysosomal protein cathepsin L is a progranulin protease
por: Lee, Chris W., et al.
Publicado: (2017) -
Cysteine protease cathepsin B mediates radiation-induced bystander effects
por: Peng, Yu, et al.
Publicado: (2017) -
Cysteine Protease Cathepsins in Atherosclerotic Cardiovascular Diseases
por: Wu, Hongxian, et al.
Publicado: (2018) -
The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease
por: Cocchiaro, Pasquale, et al.
Publicado: (2017) -
The Key Role of Lysosomal Protease Cathepsins in Viral Infections
por: Scarcella, Melania, et al.
Publicado: (2022)