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Relieving lipid accumulation through UCP1 suppresses the progression of acute kidney injury by promoting the AMPK/ULK1/autophagy pathway

Rationale: Acute kidney injury (AKI) is a serious clinical emergency with an acute onset, rapid progression, and poor prognosis. Recent evidence suggests that AKI is accompanied by significant metabolic abnormalities, including alterations in lipid metabolism. However, the specific changes in lipids...

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Detalles Bibliográficos
Autores principales: Xiong, Wei, Xiong, Zhiyong, Song, Anni, Lei, Chuntao, Ye, Chen, Zhang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978316/
https://www.ncbi.nlm.nih.gov/pubmed/33754018
http://dx.doi.org/10.7150/thno.56082