Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of keratinocytes to attenuate psoriasiform inflammation

To improve the treatment of psoriasiform inflammation, we developed actively targeted nanocarriers loaded with the phosphodiesterase 4 inhibitor AN2728. Methods: Phospholipid-poly(lactic-co-glycolic acid) nanohybrids were prepared and conjugated with monovalent anti-desmoglein 3 antibody to bind ker...

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Detalles Bibliográficos
Autores principales: Lin, Zih-Chan, Hwang, Tsong-Long, Huang, Tse-Hung, Tahara, Kohei, Trousil, Jiří, Fang, Jia-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978323/
https://www.ncbi.nlm.nih.gov/pubmed/33754014
http://dx.doi.org/10.7150/thno.56995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978323/
https://www.ncbi.nlm.nih.gov/pubmed/33754014
http://dx.doi.org/10.7150/thno.56995

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