Sequential targeting of interferon pathways for increased host resistance to bacterial superinfection during influenza

Bacterial co-infections represent a major clinical complication of influenza. Host-derived interferon (IFN) increases susceptibility to bacterial infections following influenza, but the relative roles of type-I versus type-II IFN remain poorly understood. We have used novel mouse models of co-infect...

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Detalles Bibliográficos
Autores principales: Barman, Tarani Kanta, Racine, Rachael, Bonin, Jesse L., Califano, Danielle, Salmon, Sharon L., Metzger, Dennis W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978370/
https://www.ncbi.nlm.nih.gov/pubmed/33690728
http://dx.doi.org/10.1371/journal.ppat.1009405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978370/
https://www.ncbi.nlm.nih.gov/pubmed/33690728
http://dx.doi.org/10.1371/journal.ppat.1009405

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