Cargando…
Sequential targeting of interferon pathways for increased host resistance to bacterial superinfection during influenza
Bacterial co-infections represent a major clinical complication of influenza. Host-derived interferon (IFN) increases susceptibility to bacterial infections following influenza, but the relative roles of type-I versus type-II IFN remain poorly understood. We have used novel mouse models of co-infect...
Autores principales: | Barman, Tarani Kanta, Racine, Rachael, Bonin, Jesse L., Califano, Danielle, Salmon, Sharon L., Metzger, Dennis W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978370/ https://www.ncbi.nlm.nih.gov/pubmed/33690728 http://dx.doi.org/10.1371/journal.ppat.1009405 |
Ejemplares similares
-
Viral PB1-F2 and host IFN-γ guide ILC2 and T cell activity during influenza virus infection
por: Barman, Tarani Kanta, et al.
Publicado: (2022) -
Disease Tolerance during Viral-Bacterial Co-Infections
por: Barman, Tarani Kanta, et al.
Publicado: (2021) -
Evaluation of Pneumococcal Surface Protein A as a Vaccine Antigen against Secondary Streptococcus pneumoniae Challenge during Influenza A Infection
por: Roberts, Sean, et al.
Publicado: (2019) -
TIV Vaccination Modulates Host Responses to Influenza Virus Infection that Correlate with Protection against Bacterial Superinfection
por: Choi, Angela, et al.
Publicado: (2019) -
Loss of T‐bet confers survival advantage to influenza–bacterial superinfection
por: Er, Jun Zhi, et al.
Publicado: (2018)