Cell metabolomics analyses revealed a role of altered fatty acid oxidation in neurotoxicity pattern difference between nab-paclitaxel and solvent-based paclitaxel

Peripheral neuropathy (PN) is a dose-limiting, painful adverse reaction associated with the use of paclitaxel. This common side effect was often partially attributed to the solvent used for solubilization of the highly hydrophobic drug substance. Therefore, the development of alternative formulation...

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Detalles Bibliográficos
Autores principales: Huang, Jhih-Wei, Kuo, Ching-Hua, Kuo, Han-Chun, Shih, Jin-Yuan, Tsai, Teng-Wen, Chang, Lin-Chau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978375/
https://www.ncbi.nlm.nih.gov/pubmed/33740022
http://dx.doi.org/10.1371/journal.pone.0248942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978375/
https://www.ncbi.nlm.nih.gov/pubmed/33740022
http://dx.doi.org/10.1371/journal.pone.0248942

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