Transcriptional bursts explain autosomal random monoallelic expression and affect allelic imbalance

Transcriptional bursts render substantial biological noise in cellular transcriptomes. Here, we investigated the theoretical extent of allelic expression resulting from transcriptional bursting and how it compared to the amount biallelic, monoallelic and allele-biased expression observed in single-c...

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Detalles Bibliográficos
Autores principales: Larsson, Anton J. M., Ziegenhain, Christoph, Hagemann-Jensen, Michael, Reinius, Björn, Jacob, Tina, Dalessandri, Tim, Hendriks, Gert-Jan, Kasper, Maria, Sandberg, Rickard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978379/
https://www.ncbi.nlm.nih.gov/pubmed/33690599
http://dx.doi.org/10.1371/journal.pcbi.1008772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978379/
https://www.ncbi.nlm.nih.gov/pubmed/33690599
http://dx.doi.org/10.1371/journal.pcbi.1008772

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