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Transcriptional bursts explain autosomal random monoallelic expression and affect allelic imbalance
Transcriptional bursts render substantial biological noise in cellular transcriptomes. Here, we investigated the theoretical extent of allelic expression resulting from transcriptional bursting and how it compared to the amount biallelic, monoallelic and allele-biased expression observed in single-c...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978379/ https://www.ncbi.nlm.nih.gov/pubmed/33690599 http://dx.doi.org/10.1371/journal.pcbi.1008772 |