Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity

Sequence-specific oligomers with predictable folding patterns, i.e., foldamers, provide new opportunities to mimic α-helical peptides and design inhibitors of protein-protein interactions. One major hurdle of this strategy is to retain the correct orientation of key side chains involved in protein s...

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Detalles Bibliográficos
Autores principales: Mbianda, Johanne, Bakail, May, André, Christophe, Moal, Gwenaëlle, Perrin, Marie E., Pinna, Guillaume, Guerois, Raphaël, Becher, Francois, Legrand, Pierre, Traoré, Seydou, Douat, Céline, Guichard, Gilles, Ochsenbein, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978421/
https://www.ncbi.nlm.nih.gov/pubmed/33741589
http://dx.doi.org/10.1126/sciadv.abd9153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978421/
https://www.ncbi.nlm.nih.gov/pubmed/33741589
http://dx.doi.org/10.1126/sciadv.abd9153

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