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Pain induces stable, active microcircuits in the somatosensory cortex that provide a therapeutic target

Sustained neuropathic pain from injury or inflammation remains a major burden for society. Rodent pain models have informed some cellular mechanisms increasing neuronal excitability within the spinal cord and primary somatosensory cortex (S1), but how activity patterns within these circuits change d...

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Detalles Bibliográficos
Autores principales: Okada, Takuya, Kato, Daisuke, Nomura, Yuki, Obata, Norihiko, Quan, Xiangyu, Morinaga, Akihito, Yano, Hajime, Guo, Zhongtian, Aoyama, Yuki, Tachibana, Yoshihisa, Moorhouse, Andrew J., Matoba, Osamu, Takiguchi, Tetsuya, Mizobuchi, Satoshi, Wake, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978434/
https://www.ncbi.nlm.nih.gov/pubmed/33741588
http://dx.doi.org/10.1126/sciadv.abd8261