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Pain induces stable, active microcircuits in the somatosensory cortex that provide a therapeutic target
Sustained neuropathic pain from injury or inflammation remains a major burden for society. Rodent pain models have informed some cellular mechanisms increasing neuronal excitability within the spinal cord and primary somatosensory cortex (S1), but how activity patterns within these circuits change d...
Autores principales: | Okada, Takuya, Kato, Daisuke, Nomura, Yuki, Obata, Norihiko, Quan, Xiangyu, Morinaga, Akihito, Yano, Hajime, Guo, Zhongtian, Aoyama, Yuki, Tachibana, Yoshihisa, Moorhouse, Andrew J., Matoba, Osamu, Takiguchi, Tetsuya, Mizobuchi, Satoshi, Wake, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978434/ https://www.ncbi.nlm.nih.gov/pubmed/33741588 http://dx.doi.org/10.1126/sciadv.abd8261 |
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