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New Avenues for Phosphodiesterase Inhibitors in Asthma

INTRODUCTION: Phosphodiesterases (PDEs) are isoenzymes ubiquitously expressed in the lungs where they catalyse cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (GMP), which are fundamental second messengers in asthma, thereby regulating the intracellular concentrations of the...

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Detalles Bibliográficos
Autores principales: Matera, Maria Gabriella, Ora, Josuel, Cavalli, Francesco, Rogliani, Paola, Cazzola, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979323/
https://www.ncbi.nlm.nih.gov/pubmed/33758554
http://dx.doi.org/10.2147/JEP.S242961