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Molecular Heterogeneity of Xp11.2 Translocation Renal Cell Carcinoma: The Correlation Between Split Signal Pattern in FISH and Prognosis

PURPOSE: Xp11.2 translocation renal cell carcinoma (Xp11.2 tRCC) is a distinct subtype of renal cell carcinoma (RCC) characterized by chromosomal translocations involving TFE3 gene. TFE3 break-apart fluorescence in situ hybridization (FISH) assay is an effective tool to diagnose Xp11.2 tRCC. The aim...

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Detalles Bibliográficos
Autores principales: Zhu, Yiqi, Pu, Xiaohong, Dong, Xiang, Ji, Changwei, Guo, Hongqian, Li, Dongmei, Zhao, Xiaozhi, Gan, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979328/
https://www.ncbi.nlm.nih.gov/pubmed/33758541
http://dx.doi.org/10.2147/CMAR.S297457