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The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer

Protein ubiquitination is a critical regulator of cellular homeostasis. Aberrations in the addition or removal of ubiquitin can result in the development of cancer and key components of the ubiquitination machinery serve as oncogenes or tumour suppressors. An emerging target in the development of ca...

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Detalles Bibliográficos
Autores principales: Morgan, Ethan L., Patterson, Molly R., Barba-Moreno, Diego, Scarth, James A., Wilson, Adam, Macdonald, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979541/
https://www.ncbi.nlm.nih.gov/pubmed/33627786
http://dx.doi.org/10.1038/s41388-021-01679-8