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Combination therapies utilizing neoepitope-targeted vaccines

Clinical successes have been achieved with checkpoint blockade therapy, which facilitates the function of T cells recognizing tumor-specific mutations known as neoepitopes. It is a reasonable hypothesis that therapeutic cancer vaccines targeting neoepitopes uniquely expressed by a patient’s tumor wo...

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Detalles Bibliográficos
Autores principales: Lee, Karin L., Schlom, Jeffrey, Hamilton, Duane H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979579/
https://www.ncbi.nlm.nih.gov/pubmed/33033852
http://dx.doi.org/10.1007/s00262-020-02729-y