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The role of mechanics in the growth and homeostasis of the intestinal crypt

We present a mechanical model of tissue homeostasis that is specialised to the intestinal crypt. Growth and deformation of the crypt, idealised as a line of cells on a substrate, are modelled using morphoelastic rod theory. Alternating between Lagrangian and Eulerian mechanical descriptions enables...

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Detalles Bibliográficos
Autores principales: Almet, A. A., Byrne, H. M., Maini, P. K., Moulton, D. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979635/
https://www.ncbi.nlm.nih.gov/pubmed/33219879
http://dx.doi.org/10.1007/s10237-020-01402-8