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Exact solutions and equi-dosing regimen regions for multi-dose pharmacokinetics models with transit compartments
Compartmental models which yield linear ordinary differential equations (ODEs) provide common tools for pharmacokinetics (PK) analysis, with exact solutions for drug levels or concentrations readily obtainable for low-dimensional compartment models. Exact solutions enable valuable insights and furth...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979639/ https://www.ncbi.nlm.nih.gov/pubmed/33040255 http://dx.doi.org/10.1007/s10928-020-09719-8 |