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Development of a functional salivary gland tissue chip with potential for high-content drug screening

Radiation therapy for head and neck cancers causes salivary gland dysfunction leading to permanent xerostomia. Limited progress in the discovery of new therapeutic strategies is attributed to the lack of in vitro models that mimic salivary gland function and allow high-throughput drug screening. We...

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Detalles Bibliográficos
Autores principales: Song, Yuanhui, Uchida, Hitoshi, Sharipol, Azmeer, Piraino, Lindsay, Mereness, Jared A., Ingalls, Matthew H., Rebhahn, Jonathan, Newlands, Shawn D., DeLouise, Lisa A., Ovitt, Catherine E., Benoit, Danielle S. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979686/
https://www.ncbi.nlm.nih.gov/pubmed/33742114
http://dx.doi.org/10.1038/s42003-021-01876-x