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Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1

E74-like ETS transcription factor 5 (ELF5) is involved in a wide spectrum of biological processes, e.g., mammogenesis and tumor progression. We have identified a list of p300-interacting proteins in human breast cancer cells. Among these, ELF5 was found to interact with p300 via acetylation, and the...

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Detalles Bibliográficos
Autores principales: Li, Xiahui, Li, Shujing, Li, Bowen, Li, Yanan, Aman, Sattout, Xia, Kangkai, Yang, Yuxi, Ahmad, Bashir, Wu, Huijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979705/
https://www.ncbi.nlm.nih.gov/pubmed/33742100
http://dx.doi.org/10.1038/s41698-021-00158-3